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...to start reading this and the other useful article from the beginning please click on here....Neurologic and eye disease Neurologic symptoms are the most common vaccine reaction seen in dogs. Canine distemper vaccination is the most common cause of neurologic disease, and can cause an inflammation of the brain. Measles vaccine in puppies has been reported to rarely cause damage to the nervous system. Cerebellar disease has been reported in puppies less than 5 weeks of age who were vaccinated with a modified live vaccine. Canine adenovirus-1 is known to cause an allergic uveitis (inflammation of the eye), often called 'blue eye.' Most vaccines now contain canine adenovirus-2 instead of adenovirus-1, almost eliminating the chance of blue eye occurring today.
Discomfort and swelling at the injection site Pain, swelling, redness, and irritation can occur at the injection site. These effects generally occur within 30 minutes to 1 week of the vaccination. If the signs persist, or are severe, contact your veterinarian. Occasionally, abscesses can form at the injection site. These abscesses are generally not caused by infection, but by the body's over-reaction to the vaccine.
Mild fever, decreased appetite and activity Mild fever, decreased appetite, and depression may be observed for 1-2 days following vaccination, most commonly when modified live vaccines are used. Generally, no treatment is warranted. Severe illness can occur if vaccines designed for intranasal use are accidentally injected. Severe reactions can also occur if any of a vaccine made for injection accidentally enters an animal's eyes, nose, or mouth.
Respiratory signs after intranasal vaccines Dogs vaccinated with the intranasal Bordetella and/or parainfluenza vaccine may develop a mild cough, which generally does not require treatment. They may spread the vaccine-form of the virus to other animals through their coughing.
Lameness Rarely, lameness can result from several different vaccinations. They may develop an immune-mediated arthritis in one or more joints, which is often progressive and relapses commonly occur. Dogs with this immune disorder generally have short life spans due to other complications. Hypertrophic osteodystrophy: some large-breed dogs may develop hypertrophic osteodystrophy following canine distemper vaccinations given between 2 and 5 months of age. They may also develop respiratory signs, enlarged lymph nodes, and diarrhea. The hypertrophic osteodystrophy is treated with glucocorticoids and the signs of the disease usually resolve.
Shedding of vaccine agent Vaccine virus may be found in the nasal secretions of dogs vaccinated intranasally. In addition, vaccine parvovirus is shed in the feces of vaccinated dogs, canine adenovirus-1 can be shed in the urine, and canine adenovirus-2 can be found in nasal secretions. These viruses are the vaccine forms of the virus; they do NOT revert back to the disease-causing strains.
Birth defects or infections The vaccination of pregnant animals with a modified live vaccine can result in birth defects or abortions. It is recommended that modified live vaccines NEVER be given to pregnant animals. In addition, vaccinating puppies less than 4-5 weeks of age, can actually result in them becoming infected and developing disease from modified live vaccines
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